STORM-PE and STRIKE-PE: New Data on PE Thrombectomy
STORM-PE: Functional Gains at 90 Days
In 100 randomized patients, computer assisted vacuum thrombectomy plus anticoagulation produced greater RV/LV ratio reduction, more patients reaching normal PVFS functional status, and longer six minute walk distance at 90 days versus anticoagulation alone, with comparable bleeding and safety outcomes.
STRIKE-PE Registry: Echocardiographic Recovery
Core lab reviewed echocardiograms showed TAPSE improving from 16 to 20 millimeters, TAPSE to PASP ratio rising from 0.42 to 0.57, McConnell sign resolving from 36 to 5 percent, and RV dimension shrinking from 47 to 40 millimeters by 90 days, though a subset remained non-responders.
Flash 2.0 and 3.0: Evolving Aspiration Technology
Flash’s added flow sensing alongside pressure sensing lets operators locate and aspirate thrombus without contrast runs, supporting single session bilateral treatment, shown in a 75 year old saddle PE case completed in roughly 20 minutes.
Hemolysis Safety and PERT Timing Takeaways
Porcine hemolysis data and clinical experience explain why returning aspirated blood is unnecessary despite continuous vacuum suction, while panelists emphasized that faster door to diagnosis to anticoagulation timing, coordinated through PERT teams, meaningfully affects outcomes.
