International Session: Risk Scores, Gels and Cost Analysis

Caprini Score After Varicose Vein Surgery

A 700 patient registry study found postoperative venous thromboembolism in 5.4 percent of patients, mostly asymptomatic DVT, with the Caprini score showing a weak correlation to risk and no reliable cutoff, while inpatient treatment and anticoagulation were the only significant multivariate predictors.

Hyaluronan Gel for Valve and Reflux Treatment

A pilot series described four perivenous hyaluronan gel modalities, concentric and eccentric valvuloplasty, focal venoplasty, and segmental venoplasty, achieving primary success from 76.5 to 94.7 percent in restoring valve competence and modifying flow with minimal discomfort.

Mitochondrial DNA in Varicose Vein Pathogenesis

Maria Smetanina’s study of 60 paired varicose and non-varicose vein segments found reduced mitochondrial DNA copy number and a higher proportion of mtDNA deletions in varicose veins, suggesting impaired energy metabolism contributes to venous wall remodeling.

Cost Utility of Iliofemoral DVT Treatment Strategies

Anna Louise Pouncey’s NHS model found catheter directed thrombolysis and thrombectomy cost more initially than anticoagulation but became dominant over a lifetime horizon by reducing post-thrombotic syndrome, though uncertainty around true long term costs remains.